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Thank you for taking the time to respond. Your response seems consistent to what I would have concluded. We'll see if anyone is able to chime in with any links to testing that was done in regards to this question.

I have noticed that when looking at TLD distribution of backlinks for many websites that have grown organically, the TLD distribution is somewhat consistent depending on the style of website (I am using MajesticSEO to find this distribution data). Do you feel deviating from this TLD distribution depending on the style of website you have would cause negative effects with Google? Has there been any testing of this that you know of that you can point me to (ex: building all backlinks from .info TLDs and seeing if you rank well for given keywords)?  I ask because my companies website has seen some big deviations from this and although I don't see any negative effects currently I want to make sure we create a site that stays consistent with what Google is looking for.

For example, if I look at news sites such as New York Times and Los Angeles Times, I see TLD distributions as such:

nytimes.com
.com = 59%
.gov = 14%
.org = 12%
.uk = 2%
.edu = 2%

latimes.com
.com = 59%
.org = 13%
.gov = 11%
.edu = 4%
.net = 2%
.uk = 2%

From that, if you are a news site, my assumption would be to try to stay consistent with around 55-65% of your links coming from .com domains, around 9-15% from .org, etc etc .

Now, looking at large blog styles sites I see this distribution:

naturalnews.com
.com = 70%
.org = 11%
.edu = 3%
.net = 2%
.gov = 1%

techcrunch.com
.com = 71%
.org = 10%
.edu = 4%
.net = 3%
.gov = 1%

Any input or links to tests of this would be much appreciated.