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Thanks for the response both.  That answers my question

Hey there,

Hoping someone could provide me with an answer / some insight into this.

As an example, if I were to be targeting "Fish markets in" and "Fish shops in" as my keyword(s).  And my site name was "The Fish Guide".

I am trying to populate my title tags as best as possible without sacrificing readability and definitely making an effort to avoid the the spam-factor.

Ideally I'd like to rank well (just focusing on titles at the moment, nothing else) when a user searches for "Fish markets in London" and **"Fish shops in London" **or "Fish markets in Los Angeles" or "Fish shops in Berlin" etc.

If I were to use the following structure in my titles (in this case for London):

"Fish markets and fish shops in London - The Fish Guide"

Would this work as I hope?

I.E. If a user searched for either "Fish shops in London" or "Fish markets in London" would the format of my title in this example work or would I need to have "Fish Markets in London" and "Fish Shops in London" grouped together?

E.G. "Fish Markets in London - Fish Shops in London - The Fish Guide"

Thanks!