I think he didn't reply.
He store data onto Amazon S3 and serves pictures from CDN (Amazon CloudFront). So he told me he hasn't duplicate content issues because he serves pictures.
But he tolds too "This isn't an issue for duplicate content, unlike if you were replicating your HTML".
When you use Amazon CloudFront without Amazon S3, but you use it with your webserver, Amazon CloudFront duplicates all content (pictures, pages, ...).
Onto your website, you'll only link pictures to CDN, for example http://cdn1.test.com/picture.jpg. But if GoogleBot opens http://cdn1.test.com/ it'll find all your html content !
So it'll be a duplicate issue I think, and I don't really know what is the best way to fix that (not use Amazon CloudFront without Amazon S3, Canonical, http headers, ...)
Thanks