First - stay calm. Is your traffic noticeably dropping? Have you been penalized in any way in the SERPs? If not, you might just be experiencing regular fluctuations and have nothing to worry about. Look at that first.
Next, I'm assuming you have a Pro campaign set up.
The first course of action there would be to analyze your warnings, errors and notifications to minimize those. Fix the low-hanging fruit there and move on. Next, make sure you're following proper on-page SEO architecture throughout your site. Proper titles, H1s, interlinking, hierarchy, sitemapping, etc.
Now analyze your link profile. Do you have a lot of low quality links? If so, you may need to do some cleanup.
Additionally, you're in an e-commerce sector, so you may also want to check out the most recent Pro webinar - http://www.seomoz.org/webinars/ecommerce-seo-fix-and-avoid-common-issues
There are a number of things that can contribute to this. Without more information, all I can tell you is to start with the basics and move up. Have you made any significant changes lately?