If you have not done so, consider reading. Advanced Google Adwords by Brad Geddes. I have read it twice, and reread some parts of it many times. Best book anywhere for adwords.
If you are spending major money on PPC then you must attend Brad's Adwords Seminars. This is two days of intense training for Adwords. This is not a fluffy seminar. The first morning covers the basics and then you get deep into spreadsheet math.
Adwords is not a word game, it is a math game. This is not a seminar where you will sit, sip coffee, fart and go home an expert. You are going to do lots of math that will require you to think VERY HARD. But if you can learn what is being taught you will definitely make a lot more money and your competitors will be making a lot less.
Making money with Adwords is very difficult for me. More difficult than SEO. Why? You are competing against the entire resources of your competitor. They might have lower cost inventory, cheaper shipping, cheaper labor. If they get 60% off MSRP and you get 40% off MSRP then they can spend that 20% on Adwords and still make the same profit that you do. But if you bid enough to compete with them then you lost 20% off the top, then pay credit card fees, shipping from manufacturer to you, labor, shipping supplies. You just made zero profit.
My suppliers are often the ones who bid against me on adwords. Really really hard to beat them when they have huge cost and expense advantages.
Like I say, Adwords is a game for the people are really good at math, have highly skilled people making a website that converts customers like greased pigs, and are cut-throat competitors on costs and expenses.
You better know your numbers or you will lose your shirt.