I would like to block Russian Federation, China and Ukraine spam as well as semalt and buttonsforwebsite. I have come up with the following code, what do you think?

For the countries:

BLOCK COUNTRY DOMAINS

RewriteCond %{HTTP_REFERER} .(ru|cn|ua)(/|$) [NC] 
RewriteRule .* - [F]

And for buttons-for-website.com and semalt-semalt.com:

BLOCK REFERERS

RewriteCond %{HTTP_REFERER} (semalt|buttons) [NC] 
RewriteRule .* - [F]

or should it be:

BLOCK USER AGENTS

RewriteCond %{HTTP_USER_AGENT} (semalt|buttons) [NC] 
RewriteRule .* - [F]

Could I add (semalt|buttons|o-o-6-o-o|bestwebsitesawards|humanorightswatch) or is that too many?

I have been trying to get my site into DMOZ for 15 years, without results! No idea why it is so difficult to get in, I always made sure that I followed their guidelines. My competitors have made it in, but it has been a no-go for me..

My statistics show that a large percentage of hits to my site are from Ukraine, China and the Russian Federation. Now I know for a fact that most of my demographic is from the US with a bit of Western Europe thrown in. So obviously these are spam bots. Also I have many linked pages with the .ru extension that are spammy. Should I block Ukraine, China and the Russian Federation  in my htaccess? I would think bounce rate is very high with spam bots so would that improve my SEO? Then of course there is the extremely annoying buttons-for-website.com and semalt-semalt.com!

Thank you all, I will go back to the drawing board. What is your thought on designing a separate version for mobile use?

Unfortunately my website is not mobile friendly. As it is based on clickable links within an image there is no way to adapt it either. Now, I have heard Google is getting serious about mobile friendly design, how will this impact my ratings? My current analytics show 57% desktop, 24% mobile and 19% tablet. I really like the design of my site with the clickable images and would hate to have to change it because Google says so :-(.

My website is http://tamarindobeachinfo.com