My advice is find the higher converting less competitive terms. Individuals that are search for "Denver Highlands Neighborhood Homes for Sale" are further along in their buying decision than "Denver Homes for Sale". The shorter phrases are more often window shopping. The more detailed the phrase, the more likely they will enter the store and make a purchase. Plus, if you do it right, it is much harder to get knocked knock out by a competitor when you are the first to capitalize on a unique search. If you find some gold in "Denver Lofts for Sale" then try dominating that term.
Large rivers are made up from very small streams.